Jenner publishes the results of his experiments with cowpox privately (after the Royal Society refuses to publish them). Until the end of his life he continues to promote vaccination through worldwide correspondence.
Jenner takes advantage of a local outbreak of cowpox to carry out his famous vaccination experiment on James Phipps (then 8 years old). Phipps is successfully protected against the smallpox and the history of vaccination begins.
At the age of 8, Jenner is sent to Wotton-under-Edge Grammar School, boarding with the headmaster, the Rev Thomas Clissold. He was also variolated with his classmates: a treatment in which the boys were given smallpox to protect them from future epidemics of the disease (if they survived).
His mother Sarah dies in October, following childbirth,at the age of 46. His father, the Reverend Stephen Jenner, dies in December, aged 52. He is looked after by his sisters: Mary (24), Sarah (16) and Anne (13).