John Amos Comenius explains his theory on mathetics, the science of learning, and didactics, the science of teaching using ideas of psychology and neurophysiology.
Thomas Willis publishs Pathologicae Cerebri, et Nervosi Generis Specimen expressing a new theory about the cause of epilepys using neurophysiology to explain his theory.
Edme Mariotte, a physicist and priest, discovered the blind spot of the eye commonly known as Mariotte's spot. Although he incorrectly identified the part of the eye responsible for seeing he was one of the first to document any type of neuro study.