The Arcade Fire's debut changed the face of indie rock in the 2000's like no other. Features: "Wake Up" and "Neighborhood #1 (Tunnels)" http://en.wikipedia.org/wiki/Funeral_(album)
Karen O released her screaming banshee, remaking the idea of women in modern rock music. Features "Maps" and "Date With the Night" http://en.wikipedia.org/wiki/Fever_to_Tell