Recent Event Highlights: Patients with severe asthma benefit from injections of the antibody, mepolizumab, Antibodies tackle severe asthma, ORIGINAL ARTICLE: Mepolizumab for Prednisone-Dependent Asthma with Sputum Eosinophilia, CORRESPONDENCE: Hypereosinophilic Syndrome and Mepolizumab, ORIGINAL ARTICLE: Treatment of Patients with the Hypereosinophilic Syndrome with Mepolizumab, AAAAI: Mepolizumab Can Replace Steroids in Hypereosinophilic, and 2 more...
Created by dipity on Mar 5, 2009
Last updated: 09/30/10 at 08:10 PM
Mepolizumab has no followers yet. Be the first one to follow.
Excerpt
...for use in Canada. A second study of 61 patients published in the same issue of the NEJM by British researchers also showed mepolizumab therapy effectively treats patients with very severe eosinophilic asthma. In an accompanying editorial, Dr. Sally E. Wenzel,...
Source Info
News-Medical.net
http://www.news-medical.net/?id=46524
Excerpt
...alongside mepolizumab. Professor Pavord, also chief medical advisor to the charity Asthma UK, said the results suggested mepolizumab could cut severe asthma attacks by up to 50%, as well as enabling patients to reduce their use of steroids. He added: "The...
Source Info
BBC News
http://news.bbc.co.uk/go/rss/-/1/hi/health/7922986.stm
Excerpt
...sputum were much higher in asthma patients who were getting the placebos. The numbers were close to normal with mepolizumab use. Mepolizumab, also called Bosatria, is made by GlaxoSmithKline, which provided funding for both studies. Using sputum to test eosinophil...
Source Info
ScienceNews.org
http://www.sciencenews.org/view/generic/id/41435/title/New_drug_shows_benefits_against_nasty_asthma
Excerpt
...received placebo, 9 of whom had sputum eosinophilia at the time of exacerbation. In comparison, only one patient who received mepolizumab had an asthma exacerbation, and this episode was not associated with sputum eosinophilia (P=0.002). Patients who received...
Source Info
New England Journal of Medicine -- Recent Issues
http://content.nejm.org/cgi/content/short/360/10/985?rss=1&query=recent
Excerpt
...in patients in the mepolizumab group, as compared with those in the placebo group, the safety of corticosteroid tapering with mepolizumab was not clearly demonstrated. For example, in the mepolizumab group, dyspnea and asthma occurred in 16% and 5% of patients,...
Source Info
New England Journal of Medicine -- Recent Issues
Related Topics
http://content.nejm.org/cgi/content/short/358/26/2838?rss=1&query=recent
Excerpt
...placebo (hazard ratio, 3.53; 95% CI, 1.94 to 6.45; P
http://content.nejm.org/cgi/content/short/358/12/1215?rss=1&query=recent
http://www.medpagetoday.com Marc E. Rothenberg, M.D., Ph.D., of...
Excerpt
...of Allergy and Immunology, describes positive results from an open-label phase I/2 study evaluating the safety and efficacy of mepolizumab in four adult patients with EE who had long term difficulty in swallowing and esophageal narrowing caused by chronic...
Source Info
Medical News Today
http://www.medicalnewstoday.com/medicalnews.php?newsid=59532&nfid=rssfeeds
Update Sources