Recent Event Highlights: Metabolic engineering for the production of shikimic acid in an evolved ... - 7thSpace Interactive (press release), Biotivia is giving 25% off their immune boosting supplement - Immune Edge + - SEO Press Releases™ (press release), Second Plant Pathway Could Improve Nutrition, Biofuel Production - Power Online (press release), Potential To Improve Nutrition, Biofuel Production - Medical News Today (press release), New Plant Finding Could Improve Nutrition and Biofuel Production, Second plant pathway could improve nutrition, biofuel production - PhysOrg.com, and 10 more...
Created by dipity on Aug 11, 2009
Last updated: 04/27/10 at 12:38 PM
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Metabolic engineering for the production of shikimic acid in an evolved ...7thSpace Interactive (press release)Shikimic acid (SA) is utilized in the synthesis of oseltamivir-phosphate, an anti-influenza drug. In this work, metabolic engineering approaches were ...
http://news.google.com/news/url?fd=R&sa=T&url=http%3A%2F%2F7thspace.com%2Fheadlines%2F341225%2Fmetabolic_engineering_for_the_production_of_shikimic_acid_in_an_evolved_escherichia_coli_strain_lacking_the_phosphoenolpyruvate_carbohydrate_phosphotransferase_system.html&usg=AFQjCNFweaYUsogmtqiP6B-Lw3xvab4mvw
Biotivia is giving 25% off their immune boosting supplement - Immune Edge +SEO Press Releases™ (press release)It contains: Shikimic Acid from the Star Anise fruit. It is also the natural compound from which a leading anti-viral treatment currently being distributed ...
http://news.google.com/news/url?fd=R&sa=T&url=http%3A%2F%2Fwww.seopressreleases.com%2Fbiotivia-giving-25-immune-boosting-supplement-immune-edge%2F7766&usg=AFQjCNHH7bWr-Gy--Y7HwGWEK30NnvMF1A
Second Plant Pathway Could Improve Nutrition, Biofuel ProductionPower Online (press release)Dudareva and Maeda wanted to see what would happen if they forced the shikimate pathway to function, so they gave the petunias shikimic acid. ...and more »
http://news.google.com/news/url?fd=R&sa=T&url=http%3A%2F%2Fwww.poweronline.com%2Farticle.mvc%2FSecond-Plant-Pathway-Could-Improve-Nutrition-0001&usg=AFQjCNHGKP4cOsosbWwRfmcDZGg179PtOg
Potential To Improve Nutrition, Biofuel ProductionMedical News Today (press release)Dudareva and Maeda wanted to see what would happen if they forced the shikimate pathway to function, so they gave the petunias shikimic acid. ...and more »
http://news.google.com/news/url?fd=R&sa=T&url=http%3A%2F%2Fwww.medicalnewstoday.com%2Farticles%2F184218.php&usg=AFQjCNHo70LGDn62RktY5RTcXy6PlTv1Ng
Excerpt
...and Maeda wanted to see what would happen if they forced the shikimate pathway to function, so they gave the petunias shikimic acid. The plants were flooded with the upstream compounds as expected, but since they could not use the usual arogenate pathway to...
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RedOrbit
http://www.redorbit.com/news/science/1844072/new_plant_finding_could_improve_nutrition_and_biofuel_production/index.html?source=r_science
Second plant pathway could improve nutrition, biofuel productionPhysOrg.comDudareva and Maeda wanted to see what would happen if they forced the shikimate pathway to function, so they gave the petunias shikimic acid. ...and more »
http://news.google.com/news/url?fd=R&sa=T&url=http%3A%2F%2Fwww.physorg.com%2Fnews189253827.html&usg=AFQjCNFos80hkIWe-cchUeIhTv-9d57EBQ
SW China drought may prompt Tamiflu producer to replace major ingredientPeople's Daily OnlineStar Anise is the best source of shikimic acid, an indispensable part of Tamiflu, which is used against the A/H1N1 flu, said Li Yi, secretary general of ...and more »
http://news.google.com/news/url?fd=R&sa=T&url=http%3A%2F%2Fenglish.people.com.cn%2F90001%2F90776%2F90882%2F6932375.html&usg=AFQjCNHm9TkR9iJBKO113772qP5SypKfCw
Media RoundupMyanmar TimesThe medicine was produced using Shikimic acid extracted from the Chinese star anise. The acid helps prevent the spread of the A(H1N1) virus, ...
http://news.google.com/news/url?fd=R&sa=T&url=http%3A%2F%2Fwww.mmtimes.com%2F2010%2Ftimeout%2F513%2Fmed.html&usg=AFQjCNG17boqpkvQdcNJiC36Ggj6v3muhg
Excerpt
...the Lok Sabha. The committee also expressed its displeasure over the fact the details regarding the quality and value of Shikimic acid were not reportedly available with the Director General of Commercial Intelligence. Shikimic Acid is the basic raw material...
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Zee News
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http://www.zeenews.com/articles.asp?aid=587756&sid=NAT
Industry In The Vanguard In Fight Against FluPharmiWeb.com (press release)Tamiflu's main component, shikimic acid, is isolated from a rare plant, the Chinese star anise. Every 13 grams of star anise produces just 1.3 grams of the ...and more »
http://news.google.com/news/url?fd=R&sa=T&url=http%3A%2F%2Fwww.pharmiweb.com%2Fpressreleases%2Fpressrel.asp%3FROW_ID%3D7515&usg=AFQjCNECmx9BYBB_7CoF3MpzXw0L04mqrA
VietNamNetVũ khí hữu hiệu ngăn chặn cúm A H1N1VietNamNetTrong thực tế, Tamiflu là chế phẩm của 12 công đoạn tổng hợp hoá học từ Shikimic Acid chiết xuất từ hoa hồi. Chưa có thấy có chứng cứ khoa học nào chứng tỏ ...and more »
http://news.google.com/news/url?fd=R&sa=T&url=http%3A%2F%2Fvietnamnet.vn%2Fkhoahoc%2F2009%2F07%2F861071%2F&usg=AFQjCNF0psXqkMHWY5HlRbnVDQ9bttVknA
값싼 '타미플루' 나온다헬스코리아뉴스타미플루는 원래 '스타아니스'라는 중국산 식물로부터 추출되는 쉬킴산(shikimic acid)을 원료로 합성하는데 날씨에 따라 생산량의 증감이 심한데다 타미플루의 수요 ...타미플루 저렴한 합성법 개발메디파나뉴스all 2 news articles »
http://news.google.com/news/url?fd=R&sa=T&url=http%3A%2F%2Fwww.hkn24.com%2Fnews%2FarticleView.html%3Fidxno%3D30251%26sc_sub_section_code%3DS2N2&usg=AFQjCNHnXPqIjb97uUSj9dTNA9bw5OYx4w
A comparative genomics approach to understanding the biosynthesis ...7thSpace Interactive (press release)Redundant copies of the genes coding for the key regulatory and rate-limiting enzymes of the shikimic acid pathway are found there as well. ...
http://news.google.com/news/url?fd=R&sa=T&url=http%3A%2F%2F7thspace.com%2Fheadlines%2F315339%2Fa_comparative_genomics_approach_to_understanding_the_biosynthesis_of_the_sunscreen_scytonemin_in_cyanobacteria.html&usg=AFQjCNFH7aFiITpscrqHygBt5zRjopeShg
Excerpt
... The active ingredient of Tamiflu, the drug used against swine flu, is oseltamivir. This is synthesised from shikimic acid. The first commercially viable source of this organic acid was the seed pod known as star anise, which comes from a small tree native...
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Mail & Guardian Online
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http://www.mg.co.za/article/2009-07-14-swine-flus-spicy-crisis
您可知道，傳統中草藥茴香中所含的莽草酸(Shikimic Acid)是抗病毒藥物特敏福(Tamiflu)內的主要成分。自從新型H1N1病毒爆發以來，茴香的需求在全世界內暴漲。 茴香是一種傳統的中草藥,也是中國菜肉類烹飪中常見的調味品.但很少人知道它與對抗新型H1N1病毒的藥物有關. 北京中醫藥大學教授表示：「很多人由於特敏福的關係開始關注茴香。的確，茴香含有大量特敏福中的主要成份莽草酸。」 為滿足全球需要，藥廠大亨羅氏（Roche）已經大力增加特敏福產量，而作為特敏福主要成份的茴香也成為了熱銷品。 據報導，茴香價格已經從每公斤$1.30美元上漲到$2美元。目前，全球茴香85%的產量來自於中國廣西。除了用於做菜以外，茴香在傳統中藥中也能夠治癒一些消化系統的疾病。 至今，羅氏已經為世界衛生組織提供500萬份特敏福，並且正在增加產量以應對全球需要。 其他推薦: 2009新唐人電視台全球系列大賽、中國舞、聲樂、小提琴、漢服、中國菜、鋼琴、武術、油畫、攝影competitions.ntdtv.com Divine Performing Arts 2009 World Tour www.divineshows.com 2008美國神韻藝術團全球巡迴演出盛況cntv.us
您可知道，传统中草药茴香中所含的莽草酸(Shikimic Acid)是抗病毒药物特敏福(Tamiflu)内的主要成分。自从新型H1N1病毒爆发以来，茴香的需求在全世界内暴涨。 茴香是一种传统的中草药,也是中国菜肉类烹饪中常见的调味品.但很少人知道它与对抗新型H1N1病毒的药物有关. 北京中医药大学教授表示：很多人由于特敏福的关系开始关注茴香。的确，茴香含有大量特敏福中的主要成份莽草酸。 为满足全球需要，药厂大亨罗氏（Roche）已经大力增加特敏福产量，而作为特敏福主要成份的茴香也成为了热销品。 据报导，茴香价格已经从每公斤$1.30美元上涨
what's in Tamiflu..then.....this looks at Chinese Star Anise I'm asking Science pple 2 think about how these Shikimic (sp?) acid--and--Monsanto's matching enzyme target in Round-Up ready both include Shi. Acid ... Round-Up ready Soybean Monsanto Tamiflu. Bird Flu Swine Influenza Epidemic Pandemic Vaccine Vaccination Mexico City
Excerpt
...against bird flu caused by the H5N1 virus. The fruits of the Chinese star anise tree, Illicium verum, contain 2-7 per cent shikimic acid and are an important source of the chemical. But the tree is difficult to grow, forms its first batch of fruits only in...
Source Info
Reuters Alert Net
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http://www.alertnet.org/thenews/newsdesk/scidev/123869566695.htm
Excerpt
...are looking at extracting a chemical from pine needles in Christmas trees which they say fights bird flu. Shikimic acid is used in the production of an anti-bird flu drug, Tamiflu, and is just one compound found in Sitka spruces, which are grown across Wales. They...
Source Info
BBC News
http://news.bbc.co.uk/go/rss/-/1/hi/wales/north_west/7787653.stm
Excerpt
...substrates and analogues by molecular modeling and NMR spectrometry, and structure and reactivity studies of enzymes in the shikimic acid pathway. He has received research and instrumentation grants from the National Science Foundation, the M. J. Murdock Charitable...
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PR-Inside.com
http://www.pr-inside.com/research-and-markets-organic-chemistry-student-r590816.htm
Excerpt
...scaffold with four different substituents makes up the structure of Tamiflu Currently, commercial production of Tamiflu uses shikimic acid as a staring material, which can't be synthesised economically and has to be isolated from Chinese star anise. The limited...
Source Info
Chemistry World
http://www.rsc.org/Publishing/ChemScience/Volume/2007/07/Fresh_approach_Tamiflu.asp
Excerpt
...to try them." So far, Poon and his students, using a kitchen blender, filtration and distillation to extract shikimic acid, have squeezed the equivalent of about an eighth of an ounce from a pound of sweetgum seeds, only about one-third of the yield...
Source Info
Atlanta Journal Constitution
http://www.ajc.com/services/content/metro/stories/0330metsweetgum.html?cxtype=rss&cxsvc=7&cxcat=13
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