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In 1916, Francis Rous and James Turner found that adding a Citrate Glucose solution allowed the blood to be stored for longer periods without the cells deteriorating as quickly.
In 1567, Ambroise Paré described an experiment to test the properties of the Bezoar Stone. At the time, the Bezoar Stone was commonly believed to be able to cure the effects of any poison, Paré believed this to be impossible. It happened that a cook at Paré's court was caught stealing fine silver cutlery, and was condemneed to be hanged. The cook agreed to be poisoned, on the conditions that he would be given some Bezoar straight after the poison and would go free in case he survived. The Stone did not cure him, and he died in agony seven hours after being poisoned. Thus Paré had proved that the Bezoar Stone could not cure all poisons.